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Category Archives: peptide

Peptide Therapeutics infographic

 

Posted in APIs, Fmoc, Neuland Labs, peptide, peptides, process chemistry, scale-up, synthesis | Comments Off on Peptide Therapeutics infographic

Niche Growth & Growing Niches: A Market Report on APIs and Eroom’s Law

A recent market report on APIs by Future Market Insights (FMI) paints a generally rosy economic picture of the industry over the next decade, but in this case the report’s…

Posted in API synthesis, APIs, Contract Manufacturing, drug discovery, drugs, Neuland Labs, peptide, peptides, Pharm Tech, Pharmaceutical Technology | Comments Off on Niche Growth & Growing Niches: A Market Report on APIs and Eroom’s Law

Purification of Peptides Using Surrogate Stationary Phases on Reversed-Phase Columns

Earlier this month, we published a post on Improving Quality and Yield in Solid Phase Peptide Manufacturing. In recent years, peptides have been acknowledged for their selectivity, efficacy and safety. Combined…

Posted in APIs, Chemistry, chromatography, CMC, HPLC, peptide, Peptide aggregation, peptides, RP-HPLC | Comments Off on Purification of Peptides Using Surrogate Stationary Phases on Reversed-Phase Columns

Tips for Improving Quality and Yield in Solid Phase Peptide Manufacturing

Chemical synthesis of very long peptides and certain sequences considered difficult is always a challenge. In this post, we’ll share a few practical tips for improving various critical aspects of…

Posted in analytical science, API synthesis, APIs, Chemistry, Contract Manufacturing, Fmoc, peptide, Peptide aggregation, peptides, Uncategorized | Comments Off on Tips for Improving Quality and Yield in Solid Phase Peptide Manufacturing

Analytical Prep-RP-HPLC: New Method Dramatically Improves Sample Loadability

In this post, we’ll look at a unique Prep-RP-HPLC method developed at Neuland Labs to achieve 10-fold increases in sample loadability. Despite advances in technology, there are only two ways…

Posted in Capabilities, chromatography, HPLC, Neuland Labs, peptide, peptides, RP-HPLC | Comments Off on Analytical Prep-RP-HPLC: New Method Dramatically Improves Sample Loadability

The Promise of Peptides: Developments in 3 Key Areas Reawaken Therapeutic Potential

In a post last month, we discussed the three types of peptide production techniques Neuland uses to cGMP manufacture peptide APIs and NCEs for clients. We also mentioned some of the…

Posted in APIs, Chemistry, CMC, Contract Manufacturing, drug delivery, drugs, Fmoc, Neuland Labs, peptide, Peptide aggregation, peptides, process chemistry, synthesis, Synthesis Route | Comments Off on The Promise of Peptides: Developments in 3 Key Areas Reawaken Therapeutic Potential

Advances in the Synthesis of Peptide Therapeutics: Clear Advantages…and Some Barriers

Although peptides were long passed over for drug development, recent technological advances have prompted the pharmaceutical industry to take a closer look at them. The increased sensitivity, resolution and throughput…

Posted in API synthesis, peptide, Peptide aggregation, peptides, process chemistry | Comments Off on Advances in the Synthesis of Peptide Therapeutics: Clear Advantages…and Some Barriers

Disrupting Peptide Aggregation

Earlier this month, I wrote a post about the growth of interest in peptide therapeutics. I wanted to expand on that a bit and share three common Fmoc strategies we…

Posted in Chemistry, Fmoc, peptide, Peptide aggregation, peptides, synthesis, Synthesis Route | Comments Off on Disrupting Peptide Aggregation

Peptide Process Chemistry – A New Era?

Since pioneers such as Bodanszky and Du Vigneaud first produced them synthetically in the 1950’s, peptides have always held tremendous – but unrealized – promise for human health. Despite their…

Posted in APIs, Capabilities, cardiovascular disease, Contract Manufacturing, drug delivery, genotoxic impurities, Neuland Labs, oncology, peptide, peptides, R&D, scale-up, transdermal | Comments Off on Peptide Process Chemistry – A New Era?