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Category Archives: chromatography

Video: Pharmaceutical Analytical Capabilities & Drug Quality

Drug quality and strong analytical capabilities go hand-in-hand. It is virtually impossible to achieve the former without the latter at all stages of a drug’s development and production.

Posted in API synthesis, APIs, Chemistry, chromatography, drugs, QA/QC, Quality | Tagged , , , | Comments Off on Video: Pharmaceutical Analytical Capabilities & Drug Quality

A Guide to Sourcing Pharmaceutical Peptide APIs

Rise of the Peptide Era                                                                                                                                                       Peptide synthesis has a long pharmaceutical history, stretching back to the early 1900s – and then followed by a lengthy period of dormancy….

Posted in API synthesis, APIs, Capabilities, Chemistry, chromatography, CMC, Contract Manufacturing, CRO/CMO, Fmoc, generic, HPLC, Jitsubo, Molecular Hiving, Neuland Labs, peptide, Peptide aggregation, peptides, process chemistry, Process Engineering, synthesis, Synthesis Route, TIDES | Tagged , | Comments Off on A Guide to Sourcing Pharmaceutical Peptide APIs

Purification of Peptides Using Surrogate Stationary Phases on Reversed-Phase Columns

Earlier this month, we published a post on Improving Quality and Yield in Solid Phase Peptide Manufacturing. In recent years, peptides have been acknowledged for their selectivity, efficacy and safety. Combined…

Posted in APIs, Chemistry, chromatography, CMC, HPLC, peptide, Peptide aggregation, peptides, RP-HPLC | Comments Off on Purification of Peptides Using Surrogate Stationary Phases on Reversed-Phase Columns

Emerging Trends in Analytical R&D

In the pharmaceutical discovery space, many promising analytical trends have emerged and are now on the rise – and they will see increasing use in drug discovery in coming years….

Posted in analytical science, APIs, Capabilities, Chemistry, chromatography, drug discovery, HPLC, Impurity profile, method development, process chemistry, QA/QC, Quality, R&D, RP-HPLC | Comments Off on Emerging Trends in Analytical R&D

Analytical Prep-RP-HPLC: New Method Dramatically Improves Sample Loadability

In this post, we’ll look at a unique Prep-RP-HPLC method developed at Neuland Labs to achieve 10-fold increases in sample loadability. Despite advances in technology, there are only two ways…

Posted in Capabilities, chromatography, HPLC, Neuland Labs, peptide, peptides, RP-HPLC | Comments Off on Analytical Prep-RP-HPLC: New Method Dramatically Improves Sample Loadability