Synthetic peptides are being increasingly used as therapeutics, diagnostics, for antibody production, and as tools for understanding biological processes. Our custom peptide synthesis services include production of peptides from milligrams to multi-kilogram scale by standard sequential chemical peptide syntheses and segment condensation strategies.
Our expertise include:
- solid phase peptide synthesis
- solution phase peptide synthesis
- hybrid technology for complex peptides
Most peptides between five and sixty amino acids are produced by standard solid phase peptide synthesis (SPPS) procedures. Multiple kilos of shorter length (up to 10 amino acids) are produced by solution phase methods. For longer peptides, containing up to 120 amino acids, segment condensation and ligation techniques are employed.
We have experience in enhancing the purity of peptides via salt formation, azido-peptides for click chemistry, cyclic (peptides with multiple disulfide bonds, cyclic amides) and PEGylated peptides.
Custom manufacturing solutions for peptides:
- Designing and developing manufacturing processes
- Process optimization
- Large scale, clinical trials and commercial manufacturing
- Regulatory support
- Process safety & engineering