Our expertise lies in synthesizing and modifying molecules derived from fermentation processes. We maintain the stereo genic center during chemical conversions on a large scale to minimize impurity generation.
Our team is well-versed in the design and development of synthetic routes for deuterated APIs while maintaining isotopic purity, thereby offering improved metabolic stability, reduced toxicity, and enhanced efficacy.
We can conduct catalytic hydrogenation reactions, both homogenous and heterogenous, in inert environments to enable specific hydrogenation processes. We can also undertake enantioselective reduction reactions using Rh catalysts. We have a manufacturing capacity ranging from 5 to 200 kg for hydrogenated products; a specialized cyanation manufacturing facility featuring well-established quenching/cleaning procedures; a dedicated cryogenic reactor facility capable of handling reactions at -78 °C, accommodating scales from 5 to 200 kg. We are also specialists in bromination reactions with a dedicated facility capable of manufacturing from 5 to 150 kg.
We have considerable experience in this challenging branch of organic chemistry, successfully conducting synthesis of complex carbohydrates and their related derivatives. We have a dedicated team with expertise for route scouting, POC, optimization, scale-up and purification of carbohydrate moieties from 10-100 gram at lab and 10-100 kg at scale.
We are experienced in the formation of organometallic carbon-carbon bonds, a key technique in the synthesis of complex organic molecules. Synthetic lab & manufacturing facilities are equipped with specific reactors to handle air-sensitive reaction for metal-catalysed cross-couplings.
We offer a comprehensive selection of heterocyclic building blocks that can be used in a broad range of synthetic protocols, including lithiation and palladium catalyzed cross coupling. Our dedicated facility has a capacity of 5-100 kg for producing customized solutions for heterocyclic compounds at commercial scale.
We specialize in developing and scaling up a diverse array of chiral synthesis methods for our customers. This ensures establishment of the optimal route while maintaining high quality and efficiency. We produce enantiopure pharmaceuticals with specific optical properties, covering a scale ranging from 1-100 Kg at lab to larger scales.