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Yearly Archives: 2016

Pharma APIs and India’s National Security

I’m not usually given to using clickbait-type headlines that scream “the sky is falling!”, but I came across a recent article which is a bit eye-opening for our domestic drug…

Posted in APIs, Capabilities, Chemistry, CRO/CMO, Neuland Labs, outsourcing | Comments Off on Pharma APIs and India’s National Security

API Manufacture of Deuterated Molecules

Deuterated compounds – in which a drug molecule’s carbon-hydrogen bond is replaced with a carbon deuterium bond to extend the drug’s half-life – continue to show promise in potentially boosting the…

Posted in API synthesis, APIs, CMC, Contract Manufacturing, CRO/CMO, deuterated molecule, deuteration, deuterium exchange, method development | Comments Off on API Manufacture of Deuterated Molecules

November is Alzheimer’s Disease Awareness Month in the U.S.

November is Alzheimer’s Disease Awareness Month in the U.S. Each year, Alzheimer’s Disease (AD) kills more people than breast cancer and prostate cancer combined. More worrisome is that AD is…

Posted in Alzheimers | Comments Off on November is Alzheimer’s Disease Awareness Month in the U.S.

Advantages of a Pure-Play API Contract Manufacturer

Unlike many API Contract Manufacturing firms, Neuland is pure-play, meaning we do not compete against our clients in the generic formulations market. Differentiating ourselves this way enables us to offer…

Posted in APIs, Contract Manufacturing, CRO/CMO, IP, Patent, process chemistry | Comments Off on Advantages of a Pure-Play API Contract Manufacturer

Purification of Peptides Using Surrogate Stationary Phases on Reversed-Phase Columns

Earlier this month, we published a post on Improving Quality and Yield in Solid Phase Peptide Manufacturing. In recent years, peptides have been acknowledged for their selectivity, efficacy and safety. Combined…

Posted in APIs, Chemistry, chromatography, CMC, HPLC, peptide, Peptide aggregation, peptides, RP-HPLC | Comments Off on Purification of Peptides Using Surrogate Stationary Phases on Reversed-Phase Columns

Tips for Improving Quality and Yield in Solid Phase Peptide Manufacturing

Chemical synthesis of very long peptides and certain sequences considered difficult is always a challenge. In this post, we’ll share a few practical tips for improving various critical aspects of…

Posted in analytical science, API synthesis, APIs, Chemistry, Contract Manufacturing, Fmoc, peptide, Peptide aggregation, peptides, Uncategorized | Comments Off on Tips for Improving Quality and Yield in Solid Phase Peptide Manufacturing

At ContractPharma.com: an Industry Survey and a Little Green Chemistry

I recently came across two interesting articles in recent issues of Contract Pharma. One was their annual outsourcing survey, which I find often dovetails with our experiences at Neuland. The…

Posted in Chemistry, Contract Manufacturing, ContractPharma.com, Effluent, green chemistry, process chemistry, Uncategorized, zero liquid discharge | Comments Off on At ContractPharma.com: an Industry Survey and a Little Green Chemistry

Emerging Trends in Analytical R&D

In the pharmaceutical discovery space, many promising analytical trends have emerged and are now on the rise – and they will see increasing use in drug discovery in coming years….

Posted in analytical science, APIs, Capabilities, Chemistry, chromatography, drug discovery, HPLC, Impurity profile, method development, process chemistry, QA/QC, Quality, R&D, RP-HPLC | Comments Off on Emerging Trends in Analytical R&D

APIs & Continuous Flow Manufacturing

Continuous drug manufacturing is reported to have begun with Novartis and MIT a decade ago, but no one would dare argue that it’s taken off like a rocket ship in…

Posted in API synthesis, CFM, Continuous flow manufacturing, continuous manufacturing, Contract Manufacturing, CRO/CMO, FDA | Comments Off on APIs & Continuous Flow Manufacturing

How Critical Chain Project Management (CCPM) Optimizes Pharma Innovation Timelines

In the pharma & biotech industries, Critical Chain Project Management (CCPM) plans and manages projects by emphasizing the available resources—such as people, equipment, and facilities—that can be used to complete…

Posted in CCPM, Chemistry, Critical Chain Project Management, CRO/CMO | Comments Off on How Critical Chain Project Management (CCPM) Optimizes Pharma Innovation Timelines