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Category Archives: deuteration

Deuterated Drug Molecules: Perfecting the Gamechanger

Posted on December 1, 2021 by

Scientific breakthroughs in the pharmaceutical industry can happen overnight, but it still takes time to perfect a discovery’s applications. Deuterium-labeled active pharmaceutical ingredients (APIs) are one specific advancement that has…

Posted in APIs, deuterated molecule, deuteration, deuterium exchange, drugs | Tagged , , | Comments Off on Deuterated Drug Molecules: Perfecting the Gamechanger

Deuterated Drugs Reach Two-Year Anniversary

Posted on May 15, 2019 by

We’ve reached the two year anniversary of the first FDA approval of a deuterated molecule (April 2017, Teva’s Astedo – a deuterated version of tetrabenazine for the treatment of Huntington’s…

Posted in APIs, Chemistry, CMC, Contract Manufacturing, deuterated molecule, deuteration, deuterium exchange, method development, Neuland Labs, process chemistry | Tagged , , , | Comments Off on Deuterated Drugs Reach Two-Year Anniversary

API Manufacture of Deuterated Molecules

Posted on December 4, 2016 by

Deuterated compounds – in which a drug molecule’s carbon-hydrogen bond is replaced with a carbon deuterium bond to extend the drug’s half-life – continue to show promise in potentially boosting the…

Posted in API synthesis, APIs, CMC, Contract Manufacturing, CRO/CMO, deuterated molecule, deuteration, deuterium exchange, method development | Comments Off on API Manufacture of Deuterated Molecules