The upcoming facility is located in Bonthapally village, Medak District which is approximately 65 kilometers from Hyderabad airport and spans 5 acres. Construction is currently underway, with the first slab successfully completed as of September 2025.
This greenfield facility spans across four modular units and is fully automated through a Distributed Control System (DCS), enabling seamless scale-up from tens of kilograms to over 100 kg annually. With support for more than 40 amino acid couplings and integrated technologies like precipitation, crystallization, spray drying, and lyophilization, the site is engineered to accelerate your development timelines and enhance cost-efficiency.
At Neuland, this expansion reflects our commitment to delivering reliable, high-quality peptide manufacturing solutions tailored to your evolving needs.
Highlights
High-Capacity Solid & Liquid Phase Synthesis
- 250–500 L SPPS reactors, with future expansion to 2 × 2 KL SPPS
- Up to 3 KL LPPS capacity, with infrastructure to support multiple 5 KL glass-lined reactors
Large-Scale Purification Systems
- Multiple DAC columns (45 cm and 60 cm) for high-throughput purification
- Expandable to 60 cm or 80 cm DAC systems
Flexible Drying Solutions
- 100 L and 200 L lyophilizers with isolators for controlled drying
- Agitated and pressure Nutsche filter dryers in the intermediate area
Efficient Filtration & Separation
- Tangential Flow Filtration (TFF) and ion exchange columns for enhanced purification efficiency
Advanced Analytical & R&D Capabilities
- Automated peptide synthesizer for consistent and rapid synthesis
- Tray lyophilizer with programmable recipes
- UPLC and HPLC for high-precision analysis
- Coulometry and Karl Fischer for water content analysis
- GC-MS and QTOF-HRMS for detailed molecular characterization
- Circular dichroism and fluorescence spectroscopy for structural analysis
Facility Design & Automation
- Multi-product, multi-modular setup fully automated through Distributed Control System (DCS)
- Designed to scale from tens of kilograms to over 100 kg per year
- Supports over 40 amino acid couplings
- Integrated precipitation, crystallization, spray drying, and lyophilization for faster turnaround and cost efficiency
- Equipped for solid phase synthesis, liquid phase synthesis, and global deprotection processes
Quality, Compliance & Safety
The facility is designed to operate under global cGMP standards (USFDA, EMA, PMDA) with comprehensive QA/QC systems to ensure product integrity and regulatory compliance.
Segregated suites, data integrity systems (21 CFR Part 11 compliant), and in-process controls are in place to guarantee reproducibility and safety.
Environmental and safety commitments are embedded through waste management, green chemistry practices, and EHS compliance, ensuring sustainable operations.
