Product Specifications
Active APIProduct NameDabigatran Etexilate Mesylate
CAS Registry Number872728-81-9
Molecule TypeSmall Molecule
Therapeutic CategoryAnticoagulant
Development StatusDMF Filed
Regulatory Filings
USDMFE-DMF
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Dabigatran Etexilate Mesylate API (872728-81-9) used for Anticoagulant — DMF Filed.
Small Molecule
Pharmacological Profile & Biological Activity
Dabigatran and its acyl glucuronides are competitive, direct thrombin inhibitors. Because thrombin (serine protease) enables the conversion of fibrinogen into fibrin during the coagulation cascade, its inhibition prevents the development of a thrombus. Both free and clot-bound thrombin, and thrombin-induced platelet aggregation are inhibited by the active moieties.
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