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Category Archives: Uncategorized

Quality Assurance & Control: Scaling QA & Monitoring Everything

At its core, Neuland’s philosophy is to meet or exceed quality levels defined by the customer, while also meeting stringent international standards. With multiple customer projects in the works at…

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Genotoxic Impurities – Increasing Vigilance, But Still Some Uncertainty

A genotoxic impurity (GTI) is a chemical substance that can directly or indirectly damage DNA or chromosomes and induce genetic mutations. Fifteen years ago, there were no specific guidelines for…

Posted in analytical science, API synthesis, APIs, Chemistry, CMC, critical reaction parameters, genotoxic impurities, QA/QC, Route Scouting, Uncategorized | Comments Off on Genotoxic Impurities – Increasing Vigilance, But Still Some Uncertainty

Process Chemistry Goes Beyond Scale-Up

It’s a common misconception that process chemistry refers strictly to process scale-up. While it’s true that process chemistry is a crucial component of optimizing the scale up of an active…

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Data: Love it or Hate it, It’s Getting Bigger.

Big Data Brings Insights…and Complexities I recently read an interesting article at ContractPharma.com on pharma companies leveraging Big Data to improve their contracting strategies. Our collective ability to identify, capture,…

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Green Chemistry and Benign by Design

7 ways to boost profits and reduce pharma synthesis waste At Neuland, we’re advocates of green chemistry. Not only is it better for the environment, but it’s also just logistically…

Posted in analytical science, API synthesis, APIs, atom economy, Benign-by-Design, Capabilities, Chemistry, CMC, Contract Manufacturing, EHS, energy conservation, energy effciency, green chemistry, ICH, Impurity profile, Quality, R&D, Route Design, Route Scouting, small molecule, synthesis, Synthesis Route, Uncategorized, zero liquid discharge | Comments Off on Green Chemistry and Benign by Design

Energy Conservation in Pharmaceutical API Manufacturing

Neuland’s Technology Transfer team wrote a piece that was published back in 2011 in Pharmaceutical Technology on the topic of pharma manufacturing and energy efficiency. Since its publication, the issue…

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Five Trends in API Development & Production

There have been some tremendous gains made in the pharma industry’s understanding of Active Pharmaceutical Ingredient (API)  design, and it’s reflected in the APIs currently in development around the globe….

Posted in APIs, Chemistry, CMC, Contract Manufacturing, corporate stewardship, CPP, green chemistry, PAT, QbD, Uncategorized, zero liquid discharge | Comments Off on Five Trends in API Development & Production

Welcome Back Everyone – Hope You Had a Great Summer!

I hope everyone had a great summer! We’ve certainly kept busy. We started July with our rebranding, and spent the summer manufacturing plenty of APIs, drugs and peptides. And while…

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The Contract Manufacturing & Intellectual Property Challenge: Solution? Don’t Compete With the Customer.

Intellectual property rights have always been integral to negotiations for pharmaceutical contract manufacturing services, but growing complexities surrounding global IP issues, complex science, inevitable process improvements, IT infrastructure & security,…

Posted in agreement, APIs, Contract Manufacturing, CRO/CMO, genotoxic impurities, QA/QC, Uncategorized | Comments Off on The Contract Manufacturing & Intellectual Property Challenge: Solution? Don’t Compete With the Customer.

Fine-Tuning the Reaction: Pharma Embraces Contract Chemistry

Bromination? Diazotization? Oxidation? Methylation? Niche chemistry is critical to the success of most therapeutics – whether it’s a cardiovascular, anti-fungal, anti-emetic, CNS, Parkinson’s or other drug. Pharmaceutical companies continue to…

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